Author Archives: admin

Engineering photorespiration in chloroplasts: a novel strategy for increasing biomass production

Muhammad Sarwar Khan. Photosynthetic carbon metabolism is rate limiting in C3 plants because of a competing process: photorespiration. Photorespiration lowers the energy efficiency of photosynthesis by metab….

Handmade cloning: the future way of nuclear transfer?

Gábor Vajta. The topic of this review is an alternative technique for somatic cell nuclear transfer. Removal of the zona pellucida facilitates manipulations of mammalian oocytes and early embryos, and problems….

Biomechanics approaches to studying human diseases

Gabriel Y.H. Lee, Chwee T. Lim. Nanobiomechanics has recently been identified as an emerging field that can potentially make significant contributions in the study of human diseases. Research into biomechanics at the cellular an….

Wastewater treatment: a model system for microbial ecology

Holger Daims, Michael W. Taylor, Michael Wagner. Biological wastewater treatment is among the most important biotechnological applications and, as drivers of the key processes, microorganisms are central to its success. Therefore, the study of w….

Towards the preparative and large-scale precision manufacture of virus-like particles

Leonard K. Pattenden, Anton P.J. Middelberg, Marcus Niebert, Daniel I. Lipin. Virus-like particles (VLPs) are of interest in vaccination, gene therapy and drug delivery, but their potential has yet to be fully realized. This is because existing laboratory processes, when … Continue reading

A revival of bispecific antibodies

Peter Kufer, Ralf Lutterbüse, Patrick A. Baeuerle. Bispecific antibodies usually do not occur in nature but are constructed by recombinant DNA or cell-fusion technologies. Most are designed to recruit cytotoxic effector cells of the immune system ….

Cre–lox recombination: Cre-ative tools for plant biotechnology

Larry Gilbertson. Targeted insertion and the precise deletion of DNA from transgenic plant chromosomes increase the potential of plant biotechnology for commercial applications and basic research. The Cre–lox

Biological applications of protein transduction technology

Panagiotis S Kabouridis. The impermeable nature of the cell membrane to peptides, proteins, DNA and oligonucleotides limits the therapeutic potential of these biological agents. However, the recent discovery of short cati….

Haematococcus astaxanthin: applications for human health and nutrition

Martin Guerin, Mark E Huntley, Miguel Olaizola. The carotenoid pigment astaxanthin has important applications in the nutraceutical, cosmetics, food and feed industries. Haematococcus pluvialis is the richest source of natural astaxanthin….

Organ printing: computer-aided jet-based 3D tissue engineering

Vladimir Mironov, Thomas Boland, Thomas Trusk, Gabor Forgacs, Roger R. Markwald. Tissue engineering technology promises to solve the organ transplantation crisis. However, assembly of vascularized 3D soft organs remains a big challenge. Organ printing, which we define as compu….